Data superpowers for every scientist

Data superpowers for every scientist

Data superpowers for every scientist

Data superpowers for every scientist

Easily go from ad-hoc exploration to beautiful, reusable analyses — all in the cloud, with no setup required

Easily go from ad-hoc exploration to beautiful, reusable analyses — all in the cloud, with no setup required

Easily go from ad-hoc exploration to beautiful, reusable analyses — all in the cloud, with no setup required

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Built with expertise from biotech and big tech

Built with expertise from biotech and big tech

Analyze Anything

Analyze Anything

Analyze Anything

Analyze Anything

Jumpstart your research with ready-to-run workflows.

View all workflows ->

View all workflows ->

Heatmap of showcasing a downsampled subset of data from "Repression of divergent noncoding transcription by a sequence-specifi transcription factor" (Wu, A. C. K., Patel, H., Chia, M., Moretto, F., Frith, D., Snijders, A. P., & van Werven, F. J. (2018)). This is an example or cover image showcasing capabilities of the Bulk RNA sequencing (RNAseq) template or workflow, which are often typically in FASTQ format and the ability of Mantle to run powerful pipelines, like the nf-core rnqseq pipeline, to process bioinformatics data.

Heatmap of showcasing a downsampled subset of data from "Repression of divergent noncoding transcription by a sequence-specifi transcription factor" (Wu, A. C. K., Patel, H., Chia, M., Moretto, F., Frith, D., Snijders, A. P., & van Werven, F. J. (2018)). This is an example or cover image showcasing capabilities of the Bulk RNA sequencing (RNAseq) template or workflow, which are often typically in FASTQ format and the ability of Mantle to run powerful pipelines, like the nf-core rnqseq pipeline, to process bioinformatics data.

Heatmap of showcasing a downsampled subset of data from "Repression of divergent noncoding transcription by a sequence-specifi transcription factor" (Wu, A. C. K., Patel, H., Chia, M., Moretto, F., Frith, D., Snijders, A. P., & van Werven, F. J. (2018)). This is an example or cover image showcasing capabilities of the Bulk RNA sequencing (RNAseq) template or workflow, which are often typically in FASTQ format and the ability of Mantle to run powerful pipelines, like the nf-core rnqseq pipeline, to process bioinformatics data.

Bulk RNA Sequencing ->

Identify differentially-expressed genes and more from bulk RNAseq data.

Split-screen image of spatial transcriptomics, the visualizaition and quantification of gene expression in tissue sections while maintain the context of tissue architecture. To perform sequence alignment, a reference genome is needed. One technology for spatial transcriptomics is 10x Genomics Visium which uses a slide array of spots, each containing barcoded oligonucleotides, to capture mRNA from tissue sections placed on the slide. The mRNA then undergoes high-throughput RNA sequencing. The raw results from Visium experiments include a microscopy image of the tissue slice on the Visium slide and sequencing reads in FASTQ format. In order to use this data to reveal insights into cellular microenvironments, cellular heterogeneity, and spatial relationships within tissue, the data require processing, including the typical steps taken for processing RNA sequencing reads, as well as tissue detection and determination of which barcode spots overlap with the tissue.

Split-screen image of spatial transcriptomics, the visualizaition and quantification of gene expression in tissue sections while maintain the context of tissue architecture. To perform sequence alignment, a reference genome is needed. One technology for spatial transcriptomics is 10x Genomics Visium which uses a slide array of spots, each containing barcoded oligonucleotides, to capture mRNA from tissue sections placed on the slide. The mRNA then undergoes high-throughput RNA sequencing. The raw results from Visium experiments include a microscopy image of the tissue slice on the Visium slide and sequencing reads in FASTQ format. In order to use this data to reveal insights into cellular microenvironments, cellular heterogeneity, and spatial relationships within tissue, the data require processing, including the typical steps taken for processing RNA sequencing reads, as well as tissue detection and determination of which barcode spots overlap with the tissue.

Spatial Transcriptomics ->

Gain insights into spatial gene expression patterns from 10x Genomics Visium Data.

Split-screen image of spatial transcriptomics, the visualizaition and quantification of gene expression in tissue sections while maintain the context of tissue architecture. To perform sequence alignment, a reference genome is needed. One technology for spatial transcriptomics is 10x Genomics Visium which uses a slide array of spots, each containing barcoded oligonucleotides, to capture mRNA from tissue sections placed on the slide. The mRNA then undergoes high-throughput RNA sequencing. The raw results from Visium experiments include a microscopy image of the tissue slice on the Visium slide and sequencing reads in FASTQ format. In order to use this data to reveal insights into cellular microenvironments, cellular heterogeneity, and spatial relationships within tissue, the data require processing, including the typical steps taken for processing RNA sequencing reads, as well as tissue detection and determination of which barcode spots overlap with the tissue.

Spatial Transcriptomics ->

Gain insights into spatial gene expression patterns from 10x Genomics Visium Data.

Fluorescence microscopy experiments and workflows enable researchers to visualize specific biological macromolecules in tissues or cell cultures, using probes, antibody staining, or fluorescent protein conjugation, to visualize proteins of interest.

Fluorescence microscopy experiments and workflows enable researchers to visualize specific biological macromolecules in tissues or cell cultures, using probes, antibody staining, or fluorescent protein conjugation, to visualize proteins of interest.

Imaging ->

Quantify protein localization patterns from fluorescence microscopy images.

Fluorescence microscopy experiments and workflows enable researchers to visualize specific biological macromolecules in tissues or cell cultures, using probes, antibody staining, or fluorescent protein conjugation, to visualize proteins of interest.

Imaging ->

Quantify protein localization patterns from fluorescence microscopy images.

“Mantle has been instrumental in building our data infrastructure and increasing throughput. Experiments are easily searchable and reproducible and the structure we have now allows for further growth and flexibility.”

“Mantle has been instrumental in building our data infrastructure and increasing throughput. Experiments are easily searchable and reproducible and the structure we have now allows for further growth and flexibility.”

“Mantle has been instrumental in building our data infrastructure and increasing throughput. Experiments are easily searchable and reproducible and the structure we have now allows for further growth and flexibility.”

– Founder and CEO, Cell Therapy

– Founder and CEO, Cell Therapy

Accelerate data driven discovery

Accelerate data driven discovery

Accelerate data driven discovery

Accelerate data driven discovery

A single workspace to organize, analyze, and share biological data

Python notebooks designed for science

Python notebooks designed for science

Get the best of electronic lab notebooks and Jupyter Notebooks with Mantle Notebooks

Explore Notebooks

Explore Notebooks

Shareable

Send to teammates with a just a link

Reproducible and Reusable

Environment captured by default

Centralized

Never lose an important insight

Mantle Product UI - Notebook

Mantle Product UI - Notebook

Mantle Product UI - Notebook

Data and metadata stored together

Data and metadata stored together

Organize everything in the Mantle Database so that everyone can collaborate.

Explore Database

Explore Database

Searchable

Find what you need, fast

Accessible

Explore easily, with or without code

Flexible

Takes the shape of your unique science

Mantle Product UI - Database

Mantle Product UI - Database

Mantle Product UI - Database

Powerful pipelines, ready to run

Powerful pipelines, ready to run

Analyze data with no-code Mantle Pipelines from your browser—or from a Python SDK.

Explore Pipelines

Explore Pipelines

Scalable

Easily scale from pipette to petabytes

Built for everyone

Analyze data with or without code

Traceable

Results you can take to the bank—and the FDA

Mantle Product UI - Pipeline

Mantle Product UI - Pipeline

Mantle Product UI - Pipeline

Stay connected

Stay connected

Stay connected

Stay connected

Stop copying and pasting between tools to get work done.

See all integrations ->

See all integrations ->

Benchling ->

Benchling ->

Benchling ->

AWS ->

AWS ->

AWS ->

Nextflow ->

Nextflow ->

Nextflow ->

Github ->

Github ->

Github ->

Science is better together

Science is better together

Science is better together

Science is better together

Advancing biology is critical for helping patients and the planet. At Mantle, we're committed to working together to help scientists go faster and further.

Workshops illustration

Workshops illustration

Workshops

New to Mantle? New to code? Mantle hosts free workshops virtually and in person for a wide range of interests and skill sets.

Upcoming Events ->

Upcoming Events ->

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Education illustration

Learn More

Our favorite thing about science is lifelong learning. Come learn with us by visiting our blogs and let us know what you think.

Blogs ->

Blogs ->

Discover more with your data

Mantle brings data, computation, and teams together with a single platform. Let's close the gap between data and discovery.

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Discover more with your data

Mantle brings data, computation, and teams together with a single platform. Let's close the gap between data and discovery.

Sign Up